Refractory Postsurgical Hypothyroidism in Nephrotic Syndrome

Tacrolimus for Refractory Nephrotic Syndrome

Pancytopenia and nephrotic syndrome related to autoimmune hypothyroidism

A 64-year-old woman presented to her general practitioner with a four-week history of progressive bilateral leg swelling, tiredness and dry skin. She had no significant past medical history. She was not taking any medication and there was no family history of thyroid or renal disorders. On examination she had bilateral pitting oedema up to her knees, BP was 147/81 mmHg. Initial investigation sh...

An enigmatic trio of Klinefelter's syndrome, autoimmune hypothyroidism and nephrotic syndrome.

Klinefelter's syndrome is the most common chromosomal disorder associated with testicular dysfunction and male infertility. Those affected by Klinefelter's syndrome are at increased risk of systemic lupus erythematosus, breast cancer, non-Hodgkin's lymphoma, and lung cancer. Nephrotic syndrome in association with Klinefelter's syndrome has never been reported in the literature.

Simvastatin in nephrotic syndrome. Simvastatin in Nephrotic Syndrome Study Group.

BACKGROUND Hyperlipidemia of the nephrotic syndrome is a risk factor for the development of systemic atherosclerosis, but it also may aggravate glomerulosclerosis and enhance the progression of glomerular disease. HMG-CoA reductase inhibitors are effective in reducing cardiovascular morbidity and mortality. Whether they may influence the progression of glomerular disease is not clear. The Simva...

Early Cardiac Tamponade in a Patient with Postsurgical Hypothyroidism

Pericardial effusion is a common cardiac manifestation of hypothyroidism, but effusion resulting in cardiac tamponade is extremely rare. We present a case of a 56-year-old African American woman with slurred speech and altered mental status that was initially suspected to have stroke. Her chest X-ray revealed cardiomegaly and subsequent echocardiogram showed a large pericardial effusion with ec...